U heeft gezocht op: WLD-TEC+GmbH

Catalogus nummer: (BOSSBS-2752R-FITC)

Leverancier: Bioss

Omschrijving: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-2752R-A350)

Leverancier: Bioss

Omschrijving: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

UOM: 1 * 100 µl

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Catalogus nummer: (SCRR50017.00.00/37)

Leverancier: SCHURR SCHUHVERTRIEB

Omschrijving: Dry Tec-Pur insoles offer a maximum steam absorption.

UOM: 1 * 1 PAAR

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Catalogus nummer: (ANTIA79736-96)

Leverancier: ANTIBODIES.COM

Omschrijving: Human Tec ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Tec in serum, plasma, tissue homogenates, and other biological fluids.

UOM: 1 * 1 EA

New Product Sale

Catalogus nummer: (ANTIA313619-96)

Leverancier: ANTIBODIES.COM

Omschrijving: Human Tec ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Tec in serum, plasma, and other biological fluids.

UOM: 1 * 1 EA

New Product Sale

Catalogus nummer: (ORIGTA324978)

Leverancier: OriGene

Omschrijving: Anti-TEC Rabbit Polyclonal Antibody

UOM: 1 * 400 µl

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Catalogus nummer: (CSTA4987S)

Leverancier: Cell Signaling

Omschrijving: Anti-Tec Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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 This is a MarketSource item. Additional charges may apply

Catalogus nummer: (BSBTPA2000)

Leverancier: Boster Bio

Omschrijving: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Tec (TEC) detection. Tested with WB, IHC-P in Human; Mouse; Rat.

UOM: 1 * 0,1 mg

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Catalogus nummer: (ABNOMAB10371)

Leverancier: Abnova

Omschrijving: Mouse monoclonal antibody raised against recombinant TEC.

UOM: 1 * 100 µl

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Catalogus nummer: (PRSI13-073)

Leverancier: ProSci Inc.

Omschrijving: Anti-TEC Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

New Product Sale

Catalogus nummer: (BIRBORB137879-100)

Leverancier: Biorbyt

Omschrijving: Anti-TEC Rabbit Polyclonal Antibody

UOM: 1 * 1 EA

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 This is a MarketSource item. Additional charges may apply

Catalogus nummer: (ANTIA307552-100)

Leverancier: ANTIBODIES.COM

Omschrijving: Rabbit monoclonal [ARC53949] antibody to Tec for WB with samples derived from Human, Mouse and Rat.

UOM: 1 * 100 µl

New Product Sale

Catalogus nummer: (ANTIA310221-96)

Leverancier: ANTIBODIES.COM

Omschrijving: Mouse NOR1/TEC ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse NOR1/TEC in serum, plasma, and other biological fluids.

UOM: 1 * 1 EA

New Product Sale

Catalogus nummer: (BIRBORB69042-100)

Leverancier: Biorbyt

Omschrijving: Anti-TEC Mouse Monoclonal Antibody [clone: 3A5]

UOM: 1 * 100 µl

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 This is a MarketSource item. Additional charges may apply

Catalogus nummer: (ABNOH00007006-M01)

Leverancier: Abnova

Omschrijving: Anti-TEC Mouse Monoclonal Antibody [clone: 1C11]

UOM: 1 * 1 EA

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Catalogus nummer: (BSBTA01031)

Leverancier: Boster Bio

Omschrijving: Rabbit IgG polyclonal antibody for Tec detection. Tested with WB in Human;Mouse;Rat.

UOM: 1 * 1 EA

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