U heeft gezocht op: Zinc+copper+composite

Leverancier: VARIAN

Omschrijving: Holle kathodelamp, Voor: Atomic absorbtion spectroscopy, Multi-element, ultrAA lamps coded, copper/ zinc

Catalogus nummer: (BOSSBS-0076R-A680)

Leverancier: Bioss

Omschrijving: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-0076R-A750)

Leverancier: Bioss

Omschrijving: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.

UOM: 1 * 100 µl

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Catalogus nummer: (HACHLCW902)

Leverancier: Hach

Omschrijving: Crack set for digestions of complex, colloidal or undissolved metals in water and waste water.

UOM: 1 * 50 ST

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Leverancier: MP Biomedicals

Omschrijving: Zincon is a colorimetric indicator for Zn, Cu and Hg. Reagent for the spectrophotometric determination of zinc. Simultaneous determination of zinc and copper. Used in automated flow injection analysis of zinc. As a metal indicator for EDTA titration of Zn, or for the back titration of Ca in the presence of Mg with glycoletherdiaminetertraacetic acid (GEDTA or EGTA).

MSDS

Leverancier: Thermo Orion

Omschrijving: Orion™ AQUAfast tablet reagents perform colorimetric measurements of common water parameters with convenient, rapidly dissolving tablets.

Catalogus nummer: (MDTC25-021-CI)

Leverancier: Corning

Omschrijving: Trace Elements A provides copper, zinc, iron, and selenium

UOM: 1 * 100 mL

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Leverancier: MP Biomedicals

Omschrijving: Cupric sulphate pentahydrate is a common inorganic salt used in analytical chemistry, organic synthesis, and in art to etch zinc plates.

Catalogus nummer: (PRSI30-113)

Leverancier: ProSci Inc.

Omschrijving: SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

UOM: 1 * 1 EA

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Catalogus nummer: (DECNNEUT5)

Leverancier: DECON LAB

Omschrijving: Een oppervlakteactief reinigingsmiddel en/of ontsmettingsmiddel, voor gebruik op materialen die kunnen worden gecorrodeerd, geëtst, verkleurd of verzwakt door zure of alkalische reinigingsmiddelen. Ideaal voor het reinigen van alle non-ferro metalen zoals aluminium, zink, koper, zilver en messing.

UOM: 1 * 5 L

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Leverancier: PerkinElmer

Omschrijving: Holle kathodelamp, Lumina™, Voor: Perkin-Elmer instruments, Vier elementen: koper, ijzer, mangaan, zink

Leverancier: Hach

Omschrijving: System for Analytical Quality Assurance (AQA), consisting of one combined standard/spiking solution and two round robin test solutions.

Catalogus nummer: (PRSI91-985)

Leverancier: ProSci Inc.

Omschrijving: Superoxide Dismutase [Cu-Zn] (SOD1) is a soluble cytoplasmic and mitochondrial intermembrane space protein that belongs to the Cu-Zn superoxide dismutase family. SOD1 binds copper and zinc ions and is one of three isozymes responsible for destroying free superoxide radicals in the body. SOD1 neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. The enzyme protects the cell against dangerous levels of superoxide. Zinc binding promotes dimerization and stabilizes the native form. Mutations in SOD1 cause a form of familial amyotrophic lateral sclerosis. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1) which is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis.

UOM: 1 * 1 EA

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Leverancier: Thermo Fisher Scientific

Omschrijving: Titanium nickel composite (70:30), powder -325 mesh

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Catalogus nummer: (PRSI91-588)

Leverancier: ProSci Inc.

Omschrijving: Human EN-RAGE belongs to the S100/calgranulin superfamily. There are at least 21 different S100 proteins and the protein is 100% soluble in ammonium sulfate at neutral pH. S100 proteins play a role in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.Human EN-RAGE is characterized by two EF-hand calcium-binding motifs, zinc- and copper-binding protein.S100A12 is a disulfide-linked homodimer and the interface between the two subunits is composed mostly of hydrophobic residues.Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. EN-RAGE acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. It also acts as a monocyte and mast cell chemoattractant. Moreover, it can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. It can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn2+from their active sites.

UOM: 1 * 1 EA

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Catalogus nummer: (43925-100ML-F)

Leverancier: SIGMA ALDRICH MICROSCOPY

Omschrijving: Composition: Nigrosin 100 g/l, Formalin 5 ml/l in water

UOM: 1 * 100 mL

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