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Image Unavailable-BOSSBS-3736R-A750

Anti-Claudin 6 Tyr219 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-3736R-A750)
Leverancier: Bioss
Omschrijving: Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3736R-A680

Anti-Claudin 6 Tyr219 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-3736R-A680)
Leverancier: Bioss
Omschrijving: Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3736R-A350

Anti-CLDN6 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-3736R-A350)
Leverancier: Bioss
Omschrijving: Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3736R-A488

Anti-CLDN6 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-3736R-A488)
Leverancier: Bioss
Omschrijving: Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3754R-A488

Anti-CLDN6 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-3754R-A488)
Leverancier: Bioss
Omschrijving: Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7862R-A555

Anti-FAM3C Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalogus nummer: (BOSSBS-7862R-A555)
Leverancier: Bioss
Omschrijving: ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
UOM: 1 * 100 µl
Image Unavailable-USBIZ0775G

Anti-TJP1 Rat Monoclonal Antibody [clone: 10H16]

Catalogus nummer: (USBIZ0775G)
Leverancier: US Biological
Omschrijving: Anti-TJP1 Rat Monoclonal Antibody [clone: 10H16]
UOM: 1 * 1 EA
Image Unavailable-BOSSBS-11315R-A555

Anti-SAP102 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalogus nummer: (BOSSBS-11315R-A555)
Leverancier: Bioss
Omschrijving: MPP3, also known as Discs large homolog 3 (DLG3), is a 585 amino acid protein belonging to the MAGUK family. Proteins in the MAGUK family, including CASK, ZO-1, ZO-2, p55 and MPP2, are known to regulate cell proliferation, intracellular junctions and signaling pathways by interacting with the cytoskeleton. MPP3 contains one guanylate kinase-like domain, one PDZ domain, two L27 domains and one SH3 domain. Via the PDZ domain, MMP3 interacts with the C-terminus of TSLC1. MMP3 has also been found to interact with SR-2A and SR-4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11315R-CY7

Anti-SAP102 Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-11315R-CY7)
Leverancier: Bioss
Omschrijving: MPP3, also known as Discs large homolog 3 (DLG3), is a 585 amino acid protein belonging to the MAGUK family. Proteins in the MAGUK family, including CASK, ZO-1, ZO-2, p55 and MPP2, are known to regulate cell proliferation, intracellular junctions and signaling pathways by interacting with the cytoskeleton. MPP3 contains one guanylate kinase-like domain, one PDZ domain, two L27 domains and one SH3 domain. Via the PDZ domain, MMP3 interacts with the C-terminus of TSLC1. MMP3 has also been found to interact with SR-2A and SR-4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11315R-CY3

Anti-SAP102 Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-11315R-CY3)
Leverancier: Bioss
Omschrijving: MPP3, also known as Discs large homolog 3 (DLG3), is a 585 amino acid protein belonging to the MAGUK family. Proteins in the MAGUK family, including CASK, ZO-1, ZO-2, p55 and MPP2, are known to regulate cell proliferation, intracellular junctions and signaling pathways by interacting with the cytoskeleton. MPP3 contains one guanylate kinase-like domain, one PDZ domain, two L27 domains and one SH3 domain. Via the PDZ domain, MMP3 interacts with the C-terminus of TSLC1. MMP3 has also been found to interact with SR-2A and SR-4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13698R-A488

Anti-RAGEF2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-13698R-A488)
Leverancier: Bioss
Omschrijving: RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13698R-A680

Anti-RAGEF2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-13698R-A680)
Leverancier: Bioss
Omschrijving: RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11315R-A647

Anti-SAP102 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-11315R-A647)
Leverancier: Bioss
Omschrijving: MPP3, also known as Discs large homolog 3 (DLG3), is a 585 amino acid protein belonging to the MAGUK family. Proteins in the MAGUK family, including CASK, ZO-1, ZO-2, p55 and MPP2, are known to regulate cell proliferation, intracellular junctions and signaling pathways by interacting with the cytoskeleton. MPP3 contains one guanylate kinase-like domain, one PDZ domain, two L27 domains and one SH3 domain. Via the PDZ domain, MMP3 interacts with the C-terminus of TSLC1. MMP3 has also been found to interact with SR-2A and SR-4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11315R-A680

Anti-SAP102/DLG3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-11315R-A680)
Leverancier: Bioss
Omschrijving: MPP3, also known as Discs large homolog 3 (DLG3), is a 585 amino acid protein belonging to the MAGUK family. Proteins in the MAGUK family, including CASK, ZO-1, ZO-2, p55 and MPP2, are known to regulate cell proliferation, intracellular junctions and Signalling pathways by interacting with the cytoskeleton. MPP3 contains one guanylate kinase-like domain, one PDZ domain, two L27 domains and one SH3 domain. Via the PDZ domain, MMP3 interacts with the C-terminus of TSLC1. MMP3 has also been found to interact with SR-2A and SR-4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13632R-CY3

Anti-DLG5 Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-13632R-CY3)
Leverancier: Bioss
Omschrijving: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13632R

Anti-DLG5 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-13632R)
Leverancier: Bioss
Omschrijving: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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