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Omschrijving: Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozocin, a diabetagen, is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells.

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Omschrijving: Ferric sulphate is used in dyeing as a mordant, and as a coagulant for industrial wastes. It is also used in pigments, and in pickling baths for aluminum and steel. Medically it is used as an astringent and styptic. It also acts as an important oxidative agent.

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Omschrijving: Tris has been useful as buffers in a wide variety of biological systems. Uses include pH control in vitro and in vivo for body fluids and in buffering systems for electrophoresis applications. Tris has been used as a starting material for polymers, oxazolones (with carboxylic acids) and oxazolidines (with aldehydes). Tris does not precipitate calcium salts and is of value in maintaining solubility of manganese salts. It can be used for the direct standardization of a strong acid solution; the equivalence point can be determined either potentiometrically or by use of a suitable indicator such as 3-(4-Dimethylamino-1-naphthylazo)-4-methoxybenzenesulfonic acid. It is an auxiliary material in pharmaceutical science.
Store at Room Temperature (15-30 °C). Store dessicated.

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Omschrijving: Insoluble in water. Soluble in ethanol (25 mg/ml) and acetone.

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Omschrijving: YNB media, a component of synthetic defined yeast media is a well defined composition of salts, vitamins and nitrogen source for a vigorous growth of <i>S. cerevisiae</i>.

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Omschrijving: Typically prepared as a suspension in water adjusted to pH 5,0 with acetic acid. A 1% w/v solution will appear turbid.

Catalogus nummer: (ICNA111002200)

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Omschrijving: The GeneClean® for Ancient DNA™ Kit is ideal for purification of fragmented or damaged DNA from aged or preserved samples. It is designed for isolation of up to 20 μg DNA from bone, preserved tissue, soil organisms, or animal by-products.

UOM: 1 * 1 Kit

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Omschrijving: 5-Iodo-2'-deoxyuridine (Idoxuridine) ≥99%, crystalline

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Omschrijving: Streptomycin sulphate is an aminoglucoside antibiotic in which streptidine is linked glycosidically to the disaccharide streptobiosamine. It is used to inhibit bacterial protein synthesis at the level of initiation inhibition. It inhibits gram-negative and gram-positive bacteria.

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Omschrijving: Storage: Store at +4 °C, store under nitrogen
Glutathione is the major low molecular weight thiol compound of the living plant or animal cell. It is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. The sulfhydryl (thiol) group (SH) of cysteine serves as a proton donor and is responsible for the biological activity of glutathione.
Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

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Omschrijving: Creatinine, the end product of creatine catabolism is a normal constituent of urine; daily output about 25 mg/kg body weight. The increased amounts in the urine are typically associated with substantially impaired renal function. Also found together with creatine in muscle tissues and blood. It reacts with picric acid under alkaline conditions to form a Janovski complex. The rate of formation of the colored complex, measured at 480-520 nm is proportional to the creatinine concentration.
Creatinine is a useful marker for normalizing levels of other molecules found in urine and the altered creatinine levels may be associated with conditions that result in decreased renal blood flow, such as diabetes and cardiovascular disease.

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Omschrijving: Metronidazole ia an antiprotozoal (Trichomonas), a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria.

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Omschrijving: Retinol is one of the animal forms of vitamin A. It is a diterpenoid and an alcohol.

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Omschrijving: Cryopres™ Dimethyl sulfoxide is commonly used in cell cryopreservation, along with glycerol, to prevent damage to cell membranes during freezing. USP, Ph. Eur., sterile-filtered.

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Omschrijving: Chitosan is a cationic marine polymer derived form the shells of crustaceans (e.g., crabs). MP's chitosan is a partially de-acetylated chitin formed by the reaction of chitin with concentrated alkali. Chitin is a high molecular weight linear polymer of anhydro-N-acetyl-glucosamine. Chitin occurs in nature as part of the protective coating of some invertebrates.

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Omschrijving: It has been reported that benzalkonium chloride inactivates HIV and HSV in vitro.