U heeft gezocht op: Thulium(III) nitrate pentahydrate

Omschrijving: Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.

Catalogus nummer: SHBT200-80-500UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.

Catalogus nummer: SHBT200-04-1MG

UOM: 1 * 1 mg

Leverancier: Shenandoah Biotechnology

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Omschrijving: Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.

Catalogus nummer: SHBT200-01AF-10UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS).

Catalogus nummer: SHBT100-111AF-1MG

UOM: 1 * 1 mg

Leverancier: Shenandoah Biotechnology

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Omschrijving: Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic is a critical component for embryonic stem cell culture systems and is necessary for maintaining cells in an undifferentiated state. Recombinant FGF-basic 154 is the full length FGF-basic protein encoded by the human FGF-2 gene. FGF-basic 154 is the most popular tissue culture product at Shenandoah Biotechnology, Inc. There are no detectable differences in biological activity between FGF-basic 154 and the truncated FGF-basic 147 proteins.

Catalogus nummer: SHBT100-146AF-100U

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.

Catalogus nummer: SHBT800-02-100UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins. Neurotrophins undergo paracrine and autocrine signaling to control neuronal survival, neuronal differentiation, and dendrite outgrowth. NT-4 is expressed ubiquitously and signals through the TrkB receptor tryrosine kinase.

Catalogus nummer: SHBT100-30AF-1MG

UOM: 1 * 1 mg

Leverancier: Shenandoah Biotechnology

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Omschrijving: Exodus-2, also known as CCL21 and 6Ckine, is a chemokine that is strongly produced in the human lymph nodes and spleen. Exodus-2 signals through the chemokine receptor CCR7 to regulate thymocyte and activated T cell migration. Exodus-2 also mediates the homing of lymphocytes to the lymphatic system. Human and mouse Exodus-2 proteins share greater than 85% amino acid sequence identity.

Catalogus nummer: SHBT200-32AF-10UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection.

Catalogus nummer: SHBT400-12-1MG

UOM: 1 * 1 mg

Leverancier: Shenandoah Biotechnology

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Omschrijving: IL-10 is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells.

Catalogus nummer: SHBT500-16-50UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR).

Catalogus nummer: SHBT200-53-5UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR).

Catalogus nummer: SHBT200-53AF-5UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Fibroblast growth factor 22 (FGF-22) is a mediator of synaptogenesis in the adult nervous system and functions to regulate synapse formation and maturation.

Catalogus nummer: SHBT100-68-5UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFN-γ is not cross-reactive with mouse IFN-γ.

Catalogus nummer: SHBT100-77AF-20UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Epstein-Barr virus induced gene-3 (EBI3) is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form interleukin 27 (IL-27), and with p35 to form interleukin 35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.

Catalogus nummer: SHBT100-162AF-5UG

UOM: 1 * 1 EA

Leverancier: Shenandoah Biotechnology

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Omschrijving: Cytokines for polarizing T cells into T regulatory cells. T regulatory cells (Tregs) are a subset of T cells that suppress immune function. They are characterized by the expression of CD4, CD25 and Foxp3 and are known to produce immunosuppressive cytokines TGF-β 1 and IL-10. Tregs can be cultured from naive CD4+ T cells by culturing them in the presence of IL-2 and TGF-β 1 with CD3 and CD28 stimulation. In some cases cells are also cultured with neutralizing antibodies to IL-4, IFNγ and IL-12 and/or retinoic acid.

Catalogus nummer: SHBTPB-500-10

UOM: 1 * 1 Kit

Leverancier: Shenandoah Biotechnology

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