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Catalogus nummer: (STMC10953)

Leverancier: STEMCELL Technologies

Omschrijving: Supplement for the differentiation of mouse naïve CD4+ T cells into Th1 cells.

UOM: 1 * 1 mL

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Catalogus nummer: (STMC100-0923)

Leverancier: STEMCELL Technologies

Omschrijving: For detection of active caspase-3 in mammalian cells undergoing apoptosis - 100 tests.

UOM: 1 * 100 ST

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Catalogus nummer: (STMC100-0900)

Leverancier: STEMCELL Technologies

Omschrijving: For differentiation of human ES or iPS cells to megakaryocytes and platelets.

UOM: 1 * 1 Kit

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Catalogus nummer: (STMC100-0920)

Leverancier: STEMCELL Technologies

Omschrijving: For detection of caspase-3/7 activity in cell lysates prepared from mammalian cells undergoing apoptosis - 200 tests.

UOM: 1 * 200 ST

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Catalogus nummer: (STMC17865)

Leverancier: STEMCELL Technologies

Omschrijving: Immunomagnetic positive selection of human central and effector memory CD4+ T cells.

UOM: 1 * 1 Kit

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Catalogus nummer: (STMC17869)

Leverancier: STEMCELL Technologies

Omschrijving: Immunomagnetic positive selection of human central and effector memory CD8+ T cells.

UOM: 1 * 1 Kit

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Leverancier: STEMCELL Technologies

Omschrijving: Transforming growth factor (TGF) beta 3 is a member of the TGF-β superfamily and regulates diverse cellular phenotypes. TGF-beta 3 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins, thus regulating a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (Massagué; McDowell <i>et al.</i>). TGF-beta 3 enhances glycosaminoglycan production by mesenchymal stromal cells, stimulates scar-free healing, and improves glucose tolerance and phenotypic changes in adipocyte morphology (Hall <i>et al.</i>; Holton <i>et al.</i>). TGF-beta 3 induces proliferation of posterofrontal suture-derived mesenchymal stromal cells, and stimulates expression of fibroblast growth factors 2 and 18 (James <i>et al.</i>). This product is animal component-free.

Leverancier: STEMCELL Technologies

Omschrijving: Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda <i>et al.</i>). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz <i>et al.</i>). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton <i>et al.</i>). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz <i>et al.</i>).

Catalogus nummer: (STMC100-0854)

Leverancier: STEMCELL Technologies

Omschrijving: Fluorescent dye conjugates for detection of F-actin in cell culture experiments - 300 tests.

UOM: 1 * 1 EA

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Catalogus nummer: (STMC100-0818)

Leverancier: STEMCELL Technologies

Omschrijving: Fluorescent dye conjugates for staining cell membranes of gram-positive bacteria, mammalian cells, and yeast bud scars - 1000 µg.

UOM: 1 * 1 EA

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Leverancier: STEMCELL Technologies

Omschrijving: Rat monoclonal IgG1, kappa isotype control antibody, FITC-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Interleukin 12 (IL-12p70) is a heterodimeric cytokine composed of p35 and p40 subunits. IL-12 is produced by monocytes, macrophages, dendritic cells, neutrophils and B cells in response to bacterial products and cytokines such as IFN-γ. The IL-12 receptor is expressed on T, NK, and dendritic cells. Upon binding, IL-12 initiates signaling via the JAK/STAT signaling pathway and stimulates NK, B, and T cells to produce IFN-γ (Watford <i>et al.</i>). It also regulates cytokine synthesis, proliferation of T and NK cells, and stimulates differentiation of CD4+ and CD8+ T cells (Germann and Rüde). Mice that are deficient in IL-12 are susceptible to many intracellular pathogens and have impaired IFN-γ secretion, Th1 differentiation and NK cytolytic activity; however, Th2 development and IL-4 production are enhanced (Watford <i>et al.</i>).

Catalogus nummer: (STMC79040)

Leverancier: STEMCELL Technologies

Omschrijving: For purification of RNA from cells.

UOM: 1 * 1 Kit

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Catalogus nummer: (STMC79017)

Leverancier: STEMCELL Technologies

Omschrijving: DNA ladder consisting of 13 fragments from 250 to 10000 base pairs for determining the size of double-stranded DNA by gel electrophoresis.

UOM: 1 * 600 µl

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Leverancier: STEMCELL Technologies

Omschrijving: Defined, animal component-free medium for differentiation of human ES and iPS cells to multiple lineages.

Catalogus nummer: (STMC03990)

Leverancier: STEMCELL Technologies

Omschrijving: Animal component-free suspension culture medium for human ES and iPS cells.

UOM: 1 * 1 Kit

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