Anti-CLN8 Rabbit Polyclonal Antibody

Leverancier: Bioss
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BS-11715R
BOSSBS-11715REA 725 EUR
BOSSBS-11715R
Anti-CLN8 Rabbit Polyclonal Antibody
Antilichamen
CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7More Product Information
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