Anti-ASAH1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Leverancier: Bioss
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BS-12976R-A647
BOSSBS-12976R-A647EA 893 EUR
BOSSBS-12976R-A647
Anti-ASAH1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antilichamen
Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine asMore Product Information
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