Anti-RASA1 Rabbit Polyclonal Antibody (Cy3®)

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BS-13280R-CY3
BOSSBS-13280R-CY3EA 900 EUR
BOSSBS-13280R-CY3
Anti-RASA1 Rabbit Polyclonal Antibody (Cy3®)
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The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). TheMore Product Information
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