Anti-PI3KCA Rabbit Polyclonal Antibody (Alexa Fluor® 488)

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BS-2067R-A488
BOSSBS-2067R-A488EA 901 EUR
BOSSBS-2067R-A488
Anti-PI3KCA Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antilichamen
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptorMore Product Information
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