Anti-BTK Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Leverancier: Bioss
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BS-2752R-A488
BOSSBS-2752R-A488EA 876 EUR
BOSSBS-2752R-A488
Anti-BTK Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antilichamen
Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop isMore Product Information
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