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Leverancier: Cayman Chemical
Omschrijving: Brefeldin A

Leverancier: Thermo Fisher Scientific
Omschrijving: Brefeldin A (natural)
Leverancier: TCI
Omschrijving: Brefeldin A ≥98.0% (by HPLC)

Leverancier: Apollo Scientific
Omschrijving: BFA is a macrolide antiobiotic. Disrupts mechanism of Golgi apparatus.

Leverancier: ENZO LIFE SCIENCES
Omschrijving: GEF inhibitor

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Catalogus nummer: (203729-1)
Leverancier: Merck Millipore (Calbiochem‎)
Omschrijving: Brefeldin A, Millipore®
UOM: 1 * 1 mg


Leverancier: Thermo Fisher Scientific
Omschrijving: Brefeldin A ≥99%
Leverancier: MP Biomedicals
Omschrijving: Storage: Store at -20 °C.
Brefeldin A is a fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. Produced by Penicillium brefeldianum. Blocks binding of the cytosolic coat protein b-COP and ARF to Golgi membranes mediated by protein G. Also blocks protein transportation into post-Golgi compartments. It activates the sphingomyelin cycle. Brefeldin A mediated apoptosis has been observed in human tumor cells.
Brefeldin A reversibly inhibits the intracellular translocation of proteins in eukaryotes, e.g., during transport of proteins to the cell surface for secretion or expression. It has been reported to block the response of cultured cells to cholera toxin. In HepG2 cells, BFA induces two blocks in the secretory pathway; one at the level of the endoplasmic reticulum-Golgi juncture and the other in the trans-Golgi network. Brefeldin A is used in the studies of Brefeldin A-inhibited Guanine Nucleotide-exchange Protein, BIG2, Regulates the Constitutive Release of TNFR1 Exosome-like Vesicles.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.

Catalogus nummer: (SERA15100.02)
Leverancier: Serva
Omschrijving: Brefeldin A
UOM: 1 * 5 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Catalogus nummer: (CSTA9972S)
Leverancier: Cell Signaling
Omschrijving: Brefeldin A
UOM: 1 * 5 mg

Market Source Item This is a MarketSource item. Additional charges may apply

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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