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Upstream processing for cell therapy Compared to production volumes associated with other biologics (e.g. mAbs: 2000L to 10000L) cell therapy production volumes are more commonly between 1L to 10L. Even the quality parameters are different. Instea...

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Downstream purification for mAbs Major processes including affinity ion exchange HIC and size exclusion require chromatography resins and process buffers. These products help ensure that the quality of the target mAb is maintained through each ste...

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Live Cell Apoptosis Assays NucView® fluorogenic caspase substrates for real-time apoptosis detection in live cells NucView® caspase-3 substrates are novel fluorescent probes that allow real-time detection of caspase-3/7 activity in intact cells. T...

Upstream processing for microbial-based recombinant proteins Using microbial fermentation for the development and manufacture of recombinant proteins keeps on showing advantages e.g for the expression of proteins that do not require post-translati...

Upstream processing for vaccines Optimal production of vaccines is achieved in mammalian expression and insect systems using cell lines that are anchorage-dependent or suspension enabled. For most vaccines optimal production is achieved in mammali...