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Image Unavailable-BOSSBS-11296R-A647

Anti-HSD17B4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-11296R-A647)
Leverancier: Bioss
Omschrijving: 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11296R-FITC

Anti-HSD17B4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-11296R-FITC)
Leverancier: Bioss
Omschrijving: 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11296R-A350

Anti-HSD17B4 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-11296R-A350)
Leverancier: Bioss
Omschrijving: 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11296R-A750

Anti-HSD17B4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-11296R-A750)
Leverancier: Bioss
Omschrijving: 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11296R-HRP

Anti-HSD17B4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-11296R-HRP)
Leverancier: Bioss
Omschrijving: 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6709R-CY3

Anti-PLA2G6 Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-6709R-CY3)
Leverancier: Bioss
Omschrijving: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
UOM: 1 * 100 µl
Image Unavailable-41358.FI

Aluminium ≥99.0% (metals basis), thin foil, Thickness: 8.0 µm (0.0003 in)

Leverancier: Thermo Fisher Scientific
Omschrijving: Aluminium ≥99.0% (metals basis), thin foil, Thickness: 8.0 µm (0.0003 in)

MSDS Certificaten

Image Unavailable-BOSSBS-12927R-A488

Anti-CYP20A1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-12927R-A488)
Leverancier: Bioss
Omschrijving: Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3737R-A350

Anti-PPARG Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-3737R-A350)
Leverancier: Bioss
Omschrijving: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3737R-FITC

Anti-PPARG Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-3737R-FITC)
Leverancier: Bioss
Omschrijving: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3737R-A680

Anti-PPAR Gamma ser112 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-3737R-A680)
Leverancier: Bioss
Omschrijving: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0494R-A647

Anti-ETFA Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-0494R-A647)
Leverancier: Bioss
Omschrijving: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-43428.G5

Aluminium ≥99.9995% (metals basis), draad, Puratronic®, annealed, Ø 2.0 mm (0.08 in)

Leverancier: Thermo Fisher Scientific
Omschrijving: Aluminium ≥99.9995% (metals basis), wire, Puratronic®, annealed, Ø 2.0 mm (0.08 in)

MSDS Certificaten

Image Unavailable-11375.GH

Aluminium ≥99.997% (metals basis), foil, Puratronic®, Thickness: 0.25 mm (0.01 in)

Leverancier: Thermo Fisher Scientific
Omschrijving: Aluminium ≥99.997% (metals basis), foil, Puratronic®, Thickness: 0.25 mm (0.01 in)

MSDS Certificaten

Image Unavailable-44333.G6

Aluminium ≥99.9999% (metals basis), draad, Puratronic®, annealed, Ø 0.5 mm (0.02 in)

Catalogus nummer: (44333.G6)
Leverancier: Thermo Fisher Scientific
Omschrijving: Aluminium ≥99.9999% (metals basis), wire, Puratronic®, annealed, Ø 0.5 mm (0.02 in)
UOM: 1 * 10 m

MSDS Certificaten


Image Unavailable-BOSSBS-7533R-A750

Anti-Lipin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-7533R-A750)
Leverancier: Bioss
Omschrijving: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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