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Image Unavailable-ANTIA253003-100

Anti-Bax Mouse Monoclonal Antibody [clone: SPM336]

Catalogus nummer: (ANTIA253003-100)
Leverancier: ANTIBODIES.COM
Omschrijving: Anti-Bax Mouse Monoclonal Antibody [clone: SPM336]
UOM: 1 * 1 EA

New Product


Product Image-USBIB2187-60C-HRP

Anti-BMX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (USBIB2187-60C-HRP)
Leverancier: US Biological
Omschrijving: Anti-BMX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM: 1 * 200 µl
Product Image-USBI032435-AP

Anti-BAX Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Catalogus nummer: (USBI032435-AP)
Leverancier: US Biological
Omschrijving: Anti-BAX Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM: 1 * 200 µl
Image Unavailable-BOSSBS-3055R-HRP

Anti-BTK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-3055R-HRP)
Leverancier: Bioss
Omschrijving: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3055R-A555

Anti-BTK Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalogus nummer: (BOSSBS-3055R-A555)
Leverancier: Bioss
Omschrijving: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BNUB0004-500

Anti-BAX Mouse Monoclonal Antibody (Purified) [clone: 2D2]

Leverancier: Biotium
Omschrijving: Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Image Unavailable-BNC400004-500

Anti-BAX Mouse Monoclonal Antibody (CF640R) [clone: 2D2]

Leverancier: Biotium
Omschrijving: Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Product Image-ELTN746111/36

ESD safety boots, lace-up, Lotte GTX Mid

Leverancier: ELTEN
Omschrijving: Ladies' safety boot is suitable for work in ESD sensitive or electrostatically protected areas (EPA).

Environmentally Preferable

Product Image-ABCAAB278680-20

Anti-BTK Rabbit Monoclonal Antibody [clone: BtkY223-B4]

Leverancier: Abcam
Omschrijving: Rabbit monoclonal [BtkY223-B4] to BTK (phospho Y223).

Image Unavailable-BOSSBS-5223R-FITC

Anti-BMX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-5223R-FITC)
Leverancier: Bioss
Omschrijving: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2752R-A680

Anti-BTK Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-2752R-A680)
Leverancier: Bioss
Omschrijving: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2765R-A488

Anti-BMX Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-2765R-A488)
Leverancier: Bioss
Omschrijving: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12905R-A488

Anti-BSX Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-12905R-A488)
Leverancier: Bioss
Omschrijving: BSX(Brain-specific homeobox protein homolog) may play a role in the determination and function of cell types in the brain. In brain, it is restricted to a few specific developing brain structures such as pineal gland, telencephalic septum, hypothalamic pre-mammillary body and arcuate nucleus. Bsx might be considered an important molecular marker for early embryonic stages of epiphysis development. It belongs to the distal-less homeobox family and contains 1 homeobox DNA-binding domain.
UOM: 1 * 100 µl
Product Image-USBIB0175-15A-HRP

Anti-BAX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (USBIB0175-15A-HRP)
Leverancier: US Biological
Omschrijving: Anti-BAX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM: 1 * 200 µl
Product Image-USBIB5000-01F-AP

Anti-BTK Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Catalogus nummer: (USBIB5000-01F-AP)
Leverancier: US Biological
Omschrijving: Anti-BTK Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM: 1 * 200 µl
Product Image-USBI032434-FITC

Anti-BAX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (USBI032434-FITC)
Leverancier: US Biological
Omschrijving: Anti-BAX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM: 1 * 200 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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