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Image Unavailable-BOSSBS-7342R-A555

Anti-SP3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalogus nummer: (BOSSBS-7342R-A555)
Leverancier: Bioss
Omschrijving: The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4 (SPR-1). Sp transcription factors share similar structures but do not share simi-lar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus. Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes. Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not. Sp2 only weakly binds to GT boxes. Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues. Sp1 and Sp3, but not Sp2 or Sp4, interact with E2, a regulatory element for the ∫4 subunit of neuronal nicotinic acetylcholine receptors. Sp3 is the only Sp member to inhibit Sp1 and Sp4 media
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7342R-HRP

Anti-SP3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-7342R-HRP)
Leverancier: Bioss
Omschrijving: The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4 (SPR-1). Sp transcription factors share similar structures but do not share simi-lar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus. Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes. Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not. Sp2 only weakly binds to GT boxes. Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues. Sp1 and Sp3, but not Sp2 or Sp4, interact with E2, a regulatory element for the ∫4 subunit of neuronal nicotinic acetylcholine receptors. Sp3 is the only Sp member to inhibit Sp1 and Sp4 media
UOM: 1 * 100 µl
Product Image-MEMMICH750LT02

Accessories for climatic chambers ICH series

Catalogus nummer: (MEMMICH750LT02)
Leverancier: MEMMERT
Omschrijving: Alternatieve lichtkast, met 6 UV-lampen (bereik van 315 tot 400 nm), doos van twee, ICH750L
UOM: 1 * 1 ST
Image Unavailable-BOSSBS-1990R-A647

Anti-MITF Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-1990R-A647)
Leverancier: Bioss
Omschrijving: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1990R-HRP

Anti-MITF Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-1990R-HRP)
Leverancier: Bioss
Omschrijving: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
UOM: 1 * 100 µl
Product Image-720-2081

VWR® Q Path® MicroStar III, Cassettes

Leverancier: VWR Collection
Omschrijving: Acetaal-polymeer. Geschikt voor het vasthouden en identificeren van weefselmonsters in verwerkings, inbeddings- en sectioneringsprocedures. Bestand tegen alle veelgebruikte histologische solventen. Wegwerpdeksel, geleverd in dispenser voor 500 cassettes. Verpakt per 3 dozen met 500 stuks.

Image Unavailable-TENATE21395

Racks, side up, for chest and upright freezers

Leverancier: TENAK
Omschrijving: The side up rack both fits into chest and upright freezers with a purpose to fill out the space that is left in freezers while using a regular rack.

Product Image-RATI5160036

Cryoboxes

Leverancier: RATIOLAB
Omschrijving: Cryoboxes, cardboard, for storage of cryovials at low temperatures.

Image Unavailable-BOSSBS-12412R-A647

Anti-SP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-12412R-A647)
Leverancier: Bioss
Omschrijving: Sp1 is a sequence-specific transcription factor that recognizes GGGGCGGGGC and closely related sequences, which are often referred to as GC boxes. Sp1 was initially identified as a HeLa cell-derived factor that selectively activates in vitro transcription from the SV40 promoter and binds to the multiple GC boxes in the 21-bp repeated elements in SV40. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of Sp1 appears to regulate the affinity of DNA binding. Sp1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. Evidence suggests that the early growth response gene, Erg-1 (also known as Zif268 or NGF1-A) (7), may downregulate certain mammalian gene promoters by competing with Sp1 for binding to an overlapping binding motif. The gene encoding human Sp1 maps to chromosome 12q13.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12412R

Anti-SP1 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-12412R)
Leverancier: Bioss
Omschrijving: Sp1 is a sequence-specific transcription factor that recognizes GGGGCGGGGC and closely related sequences, which are often referred to as GC boxes. Sp1 was initially identified as a HeLa cell-derived factor that selectively activates in vitro transcription from the SV40 promoter and binds to the multiple GC boxes in the 21-bp repeated elements in SV40. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of Sp1 appears to regulate the affinity of DNA binding. Sp1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. Evidence suggests that the early growth response gene, Erg-1 (also known as Zif268 or NGF1-A) (7), may downregulate certain mammalian gene promoters by competing with Sp1 for binding to an overlapping binding motif. The gene encoding human Sp1 maps to chromosome 12q13.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2835R-CY7

Anti-ASB2 Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-2835R-CY7)
Leverancier: Bioss
Omschrijving: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2835R-CY5.5

Anti-ASB2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalogus nummer: (BOSSBS-2835R-CY5.5)
Leverancier: Bioss
Omschrijving: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
UOM: 1 * 100 µl
Product Image-216-2002

VWR®, werkstationdispensers

Leverancier: VWR Collection
Omschrijving: Kristalheldere bakken voor kleine voorraadartikelen, zoals pipetpunten, buisjes, fittingen, vingerbedjes en andere kleine bulkartikelen.

Product Image-ENTEKA20280SH47C02

Wafer transport carriers, 20X series

Leverancier: ENTEGRIS
Omschrijving: High performance in a closed side wall configuration. Trends in wafer processing technology have mandated advancements in wafer carrier technology to support today's advanced semiconductor processing facilities. Wafer carriers designed for advanced wafer transport offer dramatic performance benefits over traditional low and mid-range wafer carriers.

New Product

Image Unavailable-BOSSBS-4653R

Anti-ASB10 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-4653R)
Leverancier: Bioss
Omschrijving: ASB10 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling (SOCS) family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box couples the suppressor of cytokine signalling proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.
UOM: 1 * 100 µl
Product Image-720-2189

VWR® Q Path® Microtwin, Cassettes

Leverancier: VWR Collection
Omschrijving: Acetaal-polymeer. Geschikt voor het vasthouden en identificeren van weefselmonsters in verwerkings, inbeddings- en sectioneringsprocedures. Bestand tegen alle veelgebruikte histologische solventen. Cassette met gemonteerd wegwerpdeksel, geleverd in dispenser. Cassettes met 2 compartimenten, elk met poriën van exact 0,09 mm². Verpakt in 3 dozen met 500 cassettes.

Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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