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Image Unavailable-BOSSBS-1859R-A750

Anti-NGB/neuroglobin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-1859R-A750)
Leverancier: Bioss
Omschrijving: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1859R-A680

Anti-NGB/neuroglobin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-1859R-A680)
Leverancier: Bioss
Omschrijving: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8338R-HRP

Anti-PANK2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-8338R-HRP)
Leverancier: Bioss
Omschrijving: Defects in PANK2 are the cause of neurodegeneration with brain iron accumulation type 1 (NBIA1); also known as pantothenate kinase-associated neurodegeneration (PKAN) or Hallervorden-Spatz syndrome (HSS). It is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain, primarily in the basal ganglia. Clinical manifestations include progressive muscle spasticity, hyperreflexia, muscle rigidity, dystonia, dysarthria, and intellectual deterioration which progresses to severe dementia over several years. It is clinically classified into classic, atypical, and intermediate phenotypes. Classic forms present with onset in the first decade, rapid progression, loss of independent ambulation within 15 years. Atypical forms have onset in the second decade, slow progression, maintenance of independent ambulation up to 40 years later. Intermediate forms manifest onset in the first decade with slow progression or onset in the second decade with rapid progression. Patients with early onset tend to also develop pigmentary retinopathy, whereas those with later onset tend to also have speech disorders and psychiatric features. All patients have the 'eye of the tiger' sign on brain MRI.Defects in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP). HARP is a rare syndrome with many clinical similarities to NBIA1.
UOM: 1 * 100 µl
Image Unavailable-ACSDCH0807.L1

Iron Standard Stock Solution

Catalogus nummer: (ACSDCH0807.L1)
Leverancier: CPACHEM
Omschrijving: Iron Standard, Iron standard stock solution
UOM: 1 * 100 mL

New Product


Image Unavailable-713-4083

Iron Standard Solution

Catalogus nummer: (713-4083)
Leverancier: WTW
Omschrijving: Iron Standard, Iron standard solution, 1000 mg/L
UOM: 1 * 500 mL
Image Unavailable-HIMEGRM476-500G

Ammonium iron (III) citrate, groen

Catalogus nummer: (HIMEGRM476-500G)
Leverancier: HIMEDIA
Omschrijving: Ammonium ferric citrate, has the formula (NH₄)₅[Fe(C₆H₄O₇)₂]. It is a green colour odorless solid.
UOM: 1 * 500 g

New Product


Image Unavailable-BOSSBS-5810R-A488

Anti-LTF Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-5810R-A488)
Leverancier: Bioss
Omschrijving: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
UOM: 1 * 100 µl
Product Image-ACRO423690250

Ammonium iron(III) sulphate dodecahydrate 99% ACS

Leverancier: Thermo Fisher Scientific
Omschrijving: Ammonium iron(III) sulphate dodecahydrate 99% ACS

MSDS Certificaten

Image Unavailable-ROTHX885.3

Ammonium iron(III) sulphate dodecahydrate

Leverancier: Roth Carl
Omschrijving: Ammonium iron(III) sulphate dodecahydrate

Image Unavailable-ROTHP734.1

Ammonium iron(III) sulphate dodecahydrate

Leverancier: Roth Carl
Omschrijving: Ammonium iron(III) sulphate dodecahydrate

Image Unavailable-BOSSBS-15472R-CY7

Anti-HGD Rabbit Polyclonal Antibody (Cy7)

Catalogus nummer: (BOSSBS-15472R-CY7)
Leverancier: Bioss
Omschrijving: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.
UOM: 1 * 100 µl
Image Unavailable-SPCMF1063-500GM

Iron(II) sulphate hydrate, dried powder FCC

Catalogus nummer: (SPCMF1063-500GM)
Leverancier: Spectrum Chemical
Omschrijving: Ferrous Sulfate, Dried Powder, FCC is used as an iron fortification food supplement additive. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
UOM: 1 * 500 g
Image Unavailable-13448.36

Ammonium iron(II) sulphate hexahydrate 98.5-101.5% ACS

Leverancier: Thermo Fisher Scientific
Omschrijving: Ammonium iron(II) sulphate hexahydrate 98.5-101.5% ACS

MSDS Certificaten

Image Unavailable-PRSI92-248

Human Recombinant NGAL (from E. coli)

Catalogus nummer: (PRSI92-248)
Leverancier: ProSci Inc.
Omschrijving: Neutrophil gelatinase-associated lipocalin(LCN2) is a secreted protein and belongs to the calycin superfamily. This protein is released from injured tubular cells after various damaging stimuli, is already known by nephrologists as one of the most promising biomarkers of incoming Acute Kidney Injury (AKI). Recent evidence also suggests its role as a biomarker in a variety of other renal and non-renal conditions. Moreover, recent studies seem to suggest a potential involvement of this factor also in the genesis and progression of chronic kidney diseases. NGAL is the first known mammalian protein which specifically binds organic molecules called siderophores, which are high-affinity iron chelators. NGAL, first known as an antibacterial factor of natural immunity, and an acute phase protein, is currently one of the most interesting and enigmatic proteins involved in the process of tumor development. acting as an intracellular iron carrier and protecting MMP9 from proteolytic degradation, NGAL has a clear pro-tumoral effect, as has already been observed in different tumors (e.g. breast, stomach, oesophagus, brain) in humans. In thyroid carcinomas, NGAL is strongly induced by NF-kB, an important factor involved both in tumor growth and in the link between chronic inflammation and neoplastic development. Thus, Lipocalin-2 (LCN2/NGAL) has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis.
UOM: 1 * 0,05 mg

New Product


Image Unavailable-BOSSBS-1859R-FITC

Anti-NGB Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-1859R-FITC)
Leverancier: Bioss
Omschrijving: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
UOM: 1 * 100 µl
Image Unavailable-31235-500G

Iron(III) sulphate hydrate 21-23% (Fe basis), Puriss. p.a., Fluka™

Leverancier: Honeywell Chemicals
Omschrijving: Iron(III) sulphate hydrate 21-23% (Fe basis), Puriss. p.a., Fluka™

MSDS

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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