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Image Unavailable-BOSSBS-5883R

Anti-SLC9A3R1 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-5883R)
Leverancier: Bioss
Omschrijving: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Interacts with MCC.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6672R-A488

Anti-KCNJ3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-6672R-A488)
Leverancier: Bioss
Omschrijving: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3299R-CY3

Anti-NEDD4L Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-3299R-CY3)
Leverancier: Bioss
Omschrijving: E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3907R-A647

Anti-LGMN Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-3907R-A647)
Leverancier: Bioss
Omschrijving: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3907R-A750

Anti-Legumain Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-3907R-A750)
Leverancier: Bioss
Omschrijving: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3907R-A488

Anti-LGMN Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-3907R-A488)
Leverancier: Bioss
Omschrijving: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-SARBMCE225S2S00-I

Semi-micro laboratoriumweegschalen, Cubis® II MCE

Leverancier: Sartorius Balances
Omschrijving: Cubis® II MCE semi-microbalansen met essentiële gebruikersinterface bieden een afleesbaarheid van 10 µg en een maximale weegcapaciteit tot 220 g. Wordt gebruikt voor het wegen van kleine monsterhoeveelheden tot het µg-bereik.

Image Unavailable-BOSSBS-3299R-A488

Anti-NEDD4L Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-3299R-A488)
Leverancier: Bioss
Omschrijving: E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
UOM: 1 * 100 µl
Product Image-METOL42N-1C

Shelf ledges, side and back, for shelving systems, Super Erecta®

Leverancier: Metro International
Omschrijving: For stationary or mobile installations, ledges prevent items from protruding or falling from shelves.

Image Unavailable-BOSSBS-6673R-A488

Anti-KCNJ3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-6673R-A488)
Leverancier: Bioss
Omschrijving: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13283R-CY5

Anti-GAPVD1 Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-13283R-CY5)
Leverancier: Bioss
Omschrijving: GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13479R-CY5

Anti-GNS Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-13479R-CY5)
Leverancier: Bioss
Omschrijving: GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate. A member of the sulfatase family, GNS assists in the catabolism of heparin, and binds calcium as a cofactor. GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), which is characterized by mild somatic disease and severe degeneration of the central nervous system. Subject to post-translational internal peptidase cleavage, GNS is encoded by a gene mapping to human chromosome 12q14.2 and mouse chromosome 10 D2.
UOM: 1 * 100 µl
Product Image-REST20157

Internal cross, zero dead volume, Valco®

Leverancier: Restek
Omschrijving: These internal cross are made of stainless steel. Used to connect four lines. Ideal for 1,6 mm OD tubing.

Product Image-479-2045

Opslagbuisjes, klein volume, met 2D-streepjescode, Matrix®

Leverancier: THERMO MATRIX TECHNOLOGIES
Omschrijving: Virgin klasse VI PP van medische kwaliteit. Voor opslag onder vrijwel alle laboratoriumomstandigheden, van kamertemperatuur tot de dampfase van vloeibare stikstof. Een permanente, unieke 2D-streepjescode is met een laser geëtst op de onderkant van elk buisje voor veilige identificatie en het traceren van monsters.

Environmentally Preferable

Image Unavailable-PERC09903981

Ferrules for gas chromatography

Leverancier: PerkinElmer
Omschrijving: Graphite/vespel ferrules, 2-hole: 1/8", internal Ø

Image Unavailable-ENZOBMLCA2300025

SKF-96365 hydrochloride ≥98% (by HPLC)

Leverancier: ENZO LIFE SCIENCES
Omschrijving: A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca²⁺ release. Note, in some cells SK&F 96365 can activate a novel Ca²⁺ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.

Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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