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Anti-CHAMP1 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI27-948)

Leverancier: ProSci Inc.

Omschrijving: The CD233 gene is located on chromosome 17q21-q22 and is part of the anion exchanger (AE) family. CD233 is expressed in the erythrocyte plasma membrane where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. CD233 associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of CD233. CD233 is predominantly dimeric but forms tetramers in the presence of ankyrin. Many CD233 mutations are known in man and these mutations can lead to two types of disease; destabilization of red cell membrane leading to hereditary spherocytosis, and defective kidney acid secretion leading to distal renal tubular acidosis. Other CD233 mutations that do not give rise to disease result in novel blood group antigens, which form the Diego blood group system. Southeast Asian ovalocytosis (SAO, Melanesian ovalocytosis) results from the heterozygous presence of a deletion in the CD233 protein and is common in areas where Plasmodium falciparum malaria is endemic. One CD233 null human is known also with very severe anemia and nephrocalcinosis [PROW].

UOM: 1 * 1 EA

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Lead(II) acetate trihydrate, EMSURE® ACS, Reag. Ph. Eur. for analysis, Supelco®

Leverancier: Merck

Omschrijving: Lead(II) acetate trihydrate, EMSURE® ACS, Reag. Ph. Eur. for analysis, Supelco®

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Lead(II) carbonate, EMSURE® ACS for analysis, Supelco®

Catalogus nummer: (1.07381.0250)

Leverancier: Merck

Omschrijving: Lead(II) carbonate, EMSURE® ACS for analysis, Supelco®

UOM: 1 * 250 g

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Lead(II) acetate trihydrate 99.5-103.0%, AnalaR NORMAPUR® analytical reagent

Leverancier: VWR Chemicals

Omschrijving: Lead(II) acetate trihydrate 99.5-103.0%, AnalaR NORMAPUR® analytical reagent

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Lead(II) oxide (Litharge), granular gold-, silver-free

Catalogus nummer: (029-930-11)

Leverancier: VWR Collection

Omschrijving: Litharge is a unique type of lead oxide used in the Fire Assay analysis of precious metals. It is produced from highly refined lead and offers a very low level of precious metal impurities.

UOM: 1 * 25 kg

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