U heeft gezocht op: Phenylthiohydantoin-delta-threonine

Catalogus nummer: (USBIS7973-58Y7-HRP)

Leverancier: US Biological

Omschrijving: Anti-STK11 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

UOM: 1 * 200 µl

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Catalogus nummer: (USBIS4283-30A-FITC)

Leverancier: US Biological

Omschrijving: Anti-STK19 Rabbit Polyclonal Antibody (FITC (Fluorescein))

UOM: 1 * 200 µl

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Catalogus nummer: (BOSSBS-6411R-A750)

Leverancier: Bioss

Omschrijving: CDK5 (Cyclin Dependent Kinase 5) is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression. CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-3016R-A555)

Leverancier: Bioss

Omschrijving: p44/42 MAP Kinase(Thr202); ERK (extracellular signal regulated kinase), also known as MAPK (mitogen activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, respectively. These kinases belong to a family of serine/threonine kinases that are activated upon treatment of cells with a large variety of stimuli including mitogens, hormones, growth factors, cytokines, and bioactive peptides. Cell stimulation induces the activation of a signaling cascade, the downstream effects of which have been linked to the regulation of cell growth and differentiation as well as the cytoskeleton. ERK1 and ERK2 are phosphorylated within the activation loop on both a Threonine and a Tyrosine residue (within a Thr-Glu-Tyr motif) by MEKs (MAPK/ERK kinases), thereby greatly elevating the activity of ERK1&2.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-3275R-HRP)

Leverancier: Bioss

Omschrijving: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-3276R)

Leverancier: Bioss

Omschrijving: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-15535R-A555)

Leverancier: Bioss

Omschrijving: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

UOM: 1 * 100 µl

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Leverancier: Thermo Fisher Scientific

Omschrijving: Tetrahydrofuraan, extra dry 99.85% unstabilised, AcroSeal®

Catalogus nummer: (USBI126569)

Leverancier: US Biological

Omschrijving: Anti-FADS1 Rabbit Polyclonal Antibody

UOM: 1 * 1 EA

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Catalogus nummer: (BOSSBS-12475R-A647)

Leverancier: Bioss

Omschrijving: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-12558R-A680)

Leverancier: Bioss

Omschrijving: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-5209R-CY5.5)

Leverancier: Bioss

Omschrijving: AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-dependent apoptosis.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-7597R)

Leverancier: Bioss

Omschrijving: The RIPK5 gene encodes a dual serine/threonine and tyrosine protein kinase that is expressed in multiple tissues. Multiple alternatively spliced transcript variants have been found, but the biological validity of some variants has not been determined.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-7597R-CY5.5)

Leverancier: Bioss

Omschrijving: The RIPK5 gene encodes a dual serine/threonine and tyrosine protein kinase that is expressed in multiple tissues. Multiple alternatively spliced transcript variants have been found, but the biological validity of some variants has not been determined.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-7597R-CY3)

Leverancier: Bioss

Omschrijving: The RIPK5 gene encodes a dual serine/threonine and tyrosine protein kinase that is expressed in multiple tissues. Multiple alternatively spliced transcript variants have been found, but the biological validity of some variants has not been determined.

UOM: 1 * 100 µl

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Catalogus nummer: (USBIB2673-76A-HRP)

Leverancier: US Biological

Omschrijving: Anti-BRSK2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

UOM: 1 * 200 µl

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