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Catalogus nummer: (PRSI3152)
Leverancier: ProSci Inc.
Omschrijving: PHAP Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
UOM: 1 * 1 EA


Leverancier: EHRENSTORFER
Omschrijving: Organic Standard, Desisopropyl atrazine , Verpakking: Glass bottle

Leverancier: DR MAISCH
Omschrijving: Toepassing: HPLC-kolom, Kromasil®, NH₂, Kromasil 100 column, Ø inw.: 4,6 mm, Lengte: 250 mm, Poriëngrootte: 100 Å, Partikelgrootte: 5 µm

Catalogus nummer: (MAISRS15.9AQ.S1530)
Leverancier: DR MAISCH
Omschrijving: Packed with ultra pure silica gel with state-of-the-art modifications.
UOM: 1 * 1 ST


Leverancier: Abcam
Omschrijving: Anti-DRIP130 Rabbit Monoclonal Antibody [clone: EPR17418]

Catalogus nummer: (MAIS5126283)
Leverancier: DR MAISCH
Omschrijving: Toepassing: HPLC-kolom, Platinum, HPLC column, C18-EPS, Fused silica, Ø inw.: 4,6 mm, Lengte: 250 mm, Poriëngrootte: 100 Å, Partikelgrootte: 5 µm
UOM: 1 * 1 ST

New Product


Leverancier: DR MAISCH
Omschrijving: Specifically designed for pharmaceutical and biotechnical separations. Ideal for LC-MS separations.

Catalogus nummer: (PRSI3145)
Leverancier: ProSci Inc.
Omschrijving: PHAP I Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
UOM: 1 * 1 EA


Catalogus nummer: (PRSI3151)
Leverancier: ProSci Inc.
Omschrijving: PHAP I Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
UOM: 1 * 1 EA


Catalogus nummer: (148-3177)
Leverancier: Dr. Weigert
Omschrijving: Manual cleaning of laboratory glassware in immersion baths in medical and biological research, laboratories in the food industry. Manual cleaning of cages for experimental animals by immersion.
UOM: 1 * 10 L

Catalogus nummer: (PRSI96-750)
Leverancier: ProSci Inc.
Omschrijving: Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is also known as TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2), Death receptor 5 (DR5), CD262, KILLER, is a member of the TNF-receptor superfamily, and contains an intracellular death domain. TNFRSF10B / DR-5 is widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines. TRAILR2 / CD262 / DR5 is the receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD (a death domain containing adaptor protein) of TRAIL-R2 / TNFRSF10B recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. CD262 / DR5 Promotes the activation of NF-kappa-B. DR5 is essential for ER stress-induced apoptosis and is regulated by p53/TP53.
UOM: 1 * 1 EA


Catalogus nummer: (PRSI33-952)
Leverancier: ProSci Inc.
Omschrijving: HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. [RefSeq].
UOM: 1 * 1 EA

New Product


Leverancier: Dr. Weigert
Omschrijving: For manually cleaning and pre-cleaning of laboratory glassware as well as for the cleaning of pipettes and viscometers in special washers. Especially suitable for the cleaning of laboratory glassware in water, phosphates and metal laboratories and laboratories where enzymatic and serological analyses are conducted.
Catalogus nummer: (148-3183)
Leverancier: Dr. Weigert
Omschrijving: neodisher® LaboClean UW is suitable for the automated cleaning of laboratory glassware and utensils in water analysis laboratories, in serological institutes and in the phosphates industry. Especially for laboratory glassware used for sensitive analyses, where residues of phosphorous compounds would adulterate analysis results.
UOM: 1 * 10 kg

Leverancier: DR MAISCH
Omschrijving: Reprospher media are based on a 100 Å ultrapure silica and are fully scalable from UPLC (1,9 µm particles) to preparative and process scale applications.

Catalogus nummer: (MAISPR25.30.S3046)
Leverancier: DR MAISCH
Omschrijving: Toepassing: HPLC-kolom, Prontosil, C30, Ø inw.: 4,6 mm, Lengte: 300 mm, Poriëngrootte: 200 Å, Partikelgrootte: 5 µm
UOM: 1 * 1 ST


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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