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Image Unavailable-BOSSBS-6673R

Anti-KCNJ3 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-6673R)
Leverancier: Bioss
Omschrijving: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
UOM: 1 * 100 µl
Product Image-METOMQ1854G

Shelving systems, standard, MetroMax Q®

Leverancier: Metro International
Omschrijving: MetroMax Q® grid shelves feature removable polymer shelf mats with epoxy coated frames, a more durable and cleanable alternative to traditional epoxy coated wire shelving.

Product Image-VARI9910124000

Pump tubing, internal standard kit

Leverancier: VARIAN
Omschrijving: Pompslang, PVC, internal standard kit, Kleurgecodeerde stoppen: Orange/white

Image Unavailable-BOSSBS-4897R-HRP

Anti-ACKR3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-4897R-HRP)
Leverancier: Bioss
Omschrijving: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6673R-A555

Anti-KCNJ3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalogus nummer: (BOSSBS-6673R-A555)
Leverancier: Bioss
Omschrijving: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13283R-A680

Anti-GAPVD1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-13283R-A680)
Leverancier: Bioss
Omschrijving: GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13283R-A555

Anti-GAPVD1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalogus nummer: (BOSSBS-13283R-A555)
Leverancier: Bioss
Omschrijving: GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl
Product Image-BOSSBS-15385R

Anti-GPR161 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-15385R)
Leverancier: Bioss
Omschrijving: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
UOM: 1 * 100 µl
Product Image-REST20155

Internal tee, zero dead volume, Valco®

Leverancier: Restek
Omschrijving: Internal tees are made of stainless steel are used to connect three lines. Suitable for 1,6 mm OD tubing.

Image Unavailable-BOSSBS-6673R-CY7

Anti-KCNJ3 Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-6673R-CY7)
Leverancier: Bioss
Omschrijving: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
UOM: 1 * 100 µl
Product Image-METO5Q557EG3

Shelving systems, stem castor carts with solid bottom shelves, MetroMax i®

Leverancier: Metro International
Omschrijving: Corrosion proof shelves and posts with removable polymer mats.

Image Unavailable-BOSSBS-3907R-A350

Anti-LGMN Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-3907R-A350)
Leverancier: Bioss
Omschrijving: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
UOM: 1 * 100 µl
Image Unavailable-VARI393112601

Accessories for GC/MS

Leverancier: VARIAN
Omschrijving: Gate assembly, internal ionisation source

Image Unavailable-METO1848NK4

Super Erecta® Industrial Wire Shelf, Metroseal Gray Epoxy

Catalogus nummer: (METO1848NK4)
Leverancier: Metro International
Omschrijving: Neutral aesthetic for the lab environment, now with corrosion and antimicrobial protection.
UOM: 1 * 1 ST

New Product


Product Image-METOTTE18K4

High-density shelving system, Super Erecta™ Top-Track™

Leverancier: Metro International
Omschrijving: Top-Track™ shelving system increases storage capacity up to 50% and maximises the usable storage area in a given space.

New Product

Image Unavailable-TEKMSHCBIC12X60X17

Storage cupboards with internal cabinet

Catalogus nummer: (TEKMSHCBIC12X60X17)
Leverancier: TEKNOMEK
Omschrijving: Our storage cupboard comes complete with an internal lockable cabinet.
UOM: 1 * 1 ST
Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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