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Omschrijving: Anti-KDEL Mouse Monoclonal Antibody [clone: 10C3]

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Omschrijving: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

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Catalogus nummer: (ENZOALX804167C100)

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Omschrijving: Host: Mouse, Isotype: IgM

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOALX804157BC100)

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Omschrijving: Host: Rat, Isotype: IgG1

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOALX804243C100)

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Omschrijving: Host: Mouse, Isotype: IgG1 kappa

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOALX804220R100)

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Omschrijving: Host: Mouse, Isotype: IgG3

UOM: 1 * 100 µl

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Catalogus nummer: (ENZOALX804148C100)

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Omschrijving: Host: Mouse, Isotype: IgG1

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOBMLKI5840001)

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Omschrijving: HTS-microplaat

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOALX804320C200)

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Omschrijving: Microcystins are extremely toxic compounds produced by cyanobacteria (blue-green algae), belonging to species of Microcystis, Oscillatoria, Anabaena and Nostoc. The contamination of drinking water or water of recreational areas can cause severe health problems to exposed humans and animals. Microcystins possess a cyclic heptapeptide structure of the general composition cyclo(-D-Ala-L-X-D-erythro-β-methylisoAsp-L-Y-Adda-D-iso-Glu-N-methyldehydroAla), where Adda is the unusual C20 aa 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid and X and Y are variable L-aa.

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOALX804342C100)

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Omschrijving: Host: Rat, Isotype: IgG1

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOALX804354C100)

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Omschrijving: Host: Rat, Isotype: IgG2a

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOALX804469C250)

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Omschrijving: Host: Rat, Isotype: IgG

UOM: 1 * 1 EA

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Catalogus nummer: (ENZOBMLSA4830100)

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Omschrijving: Host: Rabbit

UOM: 1 * 100 µl

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Catalogus nummer: (ENZOBPDDIA011011)

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Omschrijving: C5b-9, also known as the terminal complement complex (TCC), consists of C5b, C6, C7, C8 and C9, and it forms the membrane attack complex (MAC) as well as the non-lytic fluid-phase SC5b-9 complex (with protein S). The MAC forms channels in target cell membranes leading to cell lysis by osmotic leakage. The complexes contain neoantigens absent from the individual native components from which they are formed, and the antibody is directed against a neoepitope exposed on C9 when incorporated into the TCC.

UOM: 1 * 1 mg

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Catalogus nummer: (ENZOENZ30930)

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Omschrijving: Host: Mouse, Isotype: IgG1

UOM: 1 * 6 mL

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Omschrijving: Anti-p47Phox, NCF1 Rabbit Polyclonal Antibody

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