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Image Unavailable-BOSSBS-7974R-A680

Anti-ATX2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-7974R-A680)
Leverancier: Bioss
Omschrijving: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterised by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterised by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2. Longer expansions result in earlier onset of the disease. There are four named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7974R-A350

Anti-ATXN2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-7974R-A350)
Leverancier: Bioss
Omschrijving: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2. Longer expansions result in earlier onset of the disease. There are four named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7974R-A647

Anti-ATXN2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-7974R-A647)
Leverancier: Bioss
Omschrijving: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2. Longer expansions result in earlier onset of the disease. There are four named isoforms.
UOM: 1 * 100 µl
Product Image-HELL730009-44

Microplaten, kwarts

Catalogus nummer: (HELL730009-44)
Leverancier: HELLMA
Omschrijving: Microplates are increasingly being used in areas such as clinical chemistry and pharmaceutical research. Plastic microplates however are not suitable for all purposes. If chemical resistance, UV transmission, microscopic observation or thermal stability are required, it is better to use quartz microplates. These can be provided to the same basic dimensions as the plastic plates.
UOM: 1 * 1 ST
Product Image-113-8165

Chemobestendige schorten, BioClean-C™

Leverancier: Nitritex
Omschrijving: Deze schorten voor eenmalig gebruik zijn gemaakt van CleanTough™ stof, een spunbonded nonwoven PP stof gelamineerd met een PE film.

Image Unavailable-BOSSBS-8338R

Anti-PANK2 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-8338R)
Leverancier: Bioss
Omschrijving: Defects in PANK2 are the cause of neurodegeneration with brain iron accumulation type 1 (NBIA1); also known as pantothenate kinase-associated neurodegeneration (PKAN) or Hallervorden-Spatz syndrome (HSS). It is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain, primarily in the basal ganglia. Clinical manifestations include progressive muscle spasticity, hyperreflexia, muscle rigidity, dystonia, dysarthria, and intellectual deterioration which progresses to severe dementia over several years. It is clinically classified into classic, atypical, and intermediate phenotypes. Classic forms present with onset in the first decade, rapid progression, loss of independent ambulation within 15 years. Atypical forms have onset in the second decade, slow progression, maintenance of independent ambulation up to 40 years later. Intermediate forms manifest onset in the first decade with slow progression or onset in the second decade with rapid progression. Patients with early onset tend to also develop pigmentary retinopathy, whereas those with later onset tend to also have speech disorders and psychiatric features. All patients have the 'eye of the tiger' sign on brain MRI.Defects in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP). HARP is a rare syndrome with many clinical similarities to NBIA1.
UOM: 1 * 100 µl
Image Unavailable-ENZOENZ51030K100

eFluxx-ID® multidrug resistance assay kit

Leverancier: ENZO LIFE SCIENCES
Omschrijving: The EFLUXX-ID® Multidrug Resistance Assay Kit allows for functional detection of all three clinically relevant ABC transporter proteins MDR1 (p-glycoprotein), MRP1/2, and BCRP. The assay uses a hydrophobic, non-fluorescent compound that readily penetrates the cell membrane, where it is hydrolyzed to a hydrophilic fluorescent dye by intracellular esterases.

New Product

Image Unavailable-BNC400674-500

Anti-KRT10 Mouse Monoclonal Antibody (CF640R) [clone: LH2]

Leverancier: Biotium
Omschrijving: This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Image Unavailable-MODU397413

VITREX® Ultrasafe Safety Lancet

Catalogus nummer: (MODU397413)
Leverancier: Vitrex Medical A/S
Omschrijving: Vitrex Ultrasafe lancet is intended for blood glucose and other in vitro diagnostic tests.
UOM: 1 * 100 ST
Product Image-630-3467

Upright microscopes, Leica DM4 B and DM6 B

Leverancier: LEICA MICROSYSTEMS
Omschrijving: Increase your work efficiency with the Leica DM4 B or Leica DM6 B upright digital research microscopes. Both are ideally suited to making your work life easier in biomedical research and clinical labs alike.

Image Unavailable-BNCB0844-100

Anti-KRT10 Mouse Monoclonal Antibody (Biotin) [clone: KRT10/844]

Leverancier: Biotium
Omschrijving: This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Image Unavailable-EM0100-1KT

Embedding kit JB-4, Sigma-Aldrich®

Catalogus nummer: (EM0100-1KT)
Leverancier: SIGMA ALDRICH MICROSCOPY
Omschrijving: JB-4 is a water-soluble, GMA based, plastic resin kit intended for use in the preparation of embedded samples for high resolution light microscopy. It is a technique now widely used for research and clinical diagnosis. JB-4 yields semi-thin sections (0.5μ-2μ) with excellent morphological preservation.
UOM: 1 * 1 Kit
Image Unavailable-BNC680844-500

Anti-KRT10 Mouse Monoclonal Antibody (CF568) [clone: KRT10/844]

Leverancier: Biotium
Omschrijving: This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Product Image-113-8812

VWR®, Cleanroom-binnenkleding

Leverancier: VWR Collection
Omschrijving: Deze wegwerponderkleding, gemaakt van non-woven comfortabel SMS, bestaat uit een shirt en een broek. De set kan worden gebruikt als binnenpak of werkpak. Compatibel voor gebruik in cleanroomomgevingen van ISO-klasse 6.

Image Unavailable-BNC040844-500

Anti-KRT10 Mouse Monoclonal Antibody (CF405S) [clone: KRT10/844]

Leverancier: Biotium
Omschrijving: This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Product Image-1.15161.2504

Paraffin wax blended with synthetic polymers, Solidification point: 56-58°C, in pastille form, Histosec® embedding agent for histology, without DMSO, Sigma-Aldrich®

Leverancier: Merck
Omschrijving: Histosec® pastilles (without DMSO) is an embedding medium for histology of samples of human origin. It is a paraffin enriched with polymers, also available with the addition of DMSO (dimethyl sulfoxide). DMSO increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 - 58 °C and, within this range any specimen can be processed without fear of damage irrespective of the method used.
In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing.

MSDS

Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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