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Catalogus nummer: (STMC05590)

Leverancier: STEMCELL Technologies

Omschrijving: Defined cell culture medium for expansion of reset naïve human embryonic stem (ES) and induced pluripotent stem (iPS) cells.

UOM: 1 * 1 Kit

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Catalogus nummer: (STMC05580)

Leverancier: STEMCELL Technologies

Omschrijving: Defined medium kit for transgene-free induction of reset naïve human pluripotent stem cells - 1 Kit

UOM: 1 * 1 Kit

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Catalogus nummer: (STMC01993)

Leverancier: STEMCELL Technologies

Omschrijving: For detection and measurement of human immunoglobulin E.

UOM: 1 * 1 Kit

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Leverancier: STEMCELL Technologies

Omschrijving: Column-free immunomagnetic positive selection of human CD66b+ cells for HLA analysis.

Catalogus nummer: (STMC17965)

Leverancier: STEMCELL Technologies

Omschrijving: Immunomagnetic negative selection kit.

UOM: 1 * 1 Kit

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Leverancier: STEMCELL Technologies

Omschrijving: Column-free immunomagnetic positive selection of human B cells for HLA analysis.

Leverancier: STEMCELL Technologies

Omschrijving: Immunomagnetic positive selection of human CD33+ and CD66+ cells (e.g. myeloid cells).

Catalogus nummer: (STMC19868)

Leverancier: STEMCELL Technologies

Omschrijving: Immunomagnetic isolation of untouched mouse epithelial cells

UOM: 1 * 1 Kit

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Catalogus nummer: (STMC100-0195)

Leverancier: STEMCELL Technologies

Omschrijving: Serum-free media for generation and maturation of branching lung organoids from human ES and iPS cells.

UOM: 1 * 1 Kit

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Catalogus nummer: (STMC100-0074)

Leverancier: STEMCELL Technologies

Omschrijving: For differentiation of human ES or iPS cells into erythroid progenitor cells.

UOM: 1 * 1 Kit

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Leverancier: STEMCELL Technologies

Omschrijving: A cellular protein for detection of apoptotic cells, APC-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: The principal physiological regulator of erythropoiesis, Erythropoietin (EPO) is a glycoprotein growth factor that is produced primarily in the kidney in response to hypoxia or anemia. EPO promotes erythropoiesis by binding to a homodimeric cell surface receptor that activates JAK2/STAT5, PI3K/AKT, and MAPK pathways, and stimulates the proliferation and differentiation of erythroid progenitor cells (Jelkmann. Transfus Med Hemother, 2013; Kuhrt and Wojchowski. Blood, 2015).

Leverancier: STEMCELL Technologies

Omschrijving: Betacellulin is a member of the epidermal growth factor (EGF) family, and signals through EGF receptor and ERBB4. It activates ERK and AKT pathways, which induces neural stem cell proliferation and prevents spontaneous differentiation in culture. Betacellulin stimulates the expansion of neural stem cells, transit-amplifying cells, and neuroblasts derived from subventricular zone and dentate gyrus (Gómez-Gaviro <i>et al.</i>). It is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin down-regulates E-cadherin expression in ovarian cancer cell lines via MEK/ERK1/2 and PI3K/AKT signaling pathways, thus increasing cell migration (Zhao <i>et al.</i>). It is a modulator of interferon (IFN) response and enhances anti-viral effects of IFN (Al-Yahya <i>et al.</i>). Betacellulin is expressed in pancreatic α cells, β cells, and duct cells. It induces the proliferation of pancreatic cancer cell lines, inhibits apoptosis, promotes the neogenesis of β cells, and converts non-β cells into insulin-producing cells (Kawaguchi <i>et al.</i>; Miyagawa al.; Saito <i>et al.</i>).

Leverancier: STEMCELL Technologies

Omschrijving: Stromal cell-derived factor 1 alpha (SDF-1α) is a member of the CXC group of chemokines that binds to the G-protein coupled receptor, CXCR4, to regulate migration, proliferation, differentiation, and survival of many cell types including hematopoietic stem cells, B cells, and T cells. It is produced by bone marrow stromal cells, osteoblasts, endothelial cells, and neuronal cells. SDF-1α was first identified as the pre-B-cell growth-stimulating factor (PBSF) in the mouse bone marrow-derived stromal cell line, PA6, in the growth of B cell precursors (Hayashi <i>et al.</i>). SDF-1α primarily regulates cell motility during development and adulthood, including the homing of hematopoietic stem cells and neutrophils to fetal bone marrow during ontogeny (Ara <i>et al.</i> 2003a) and the recruitment of endothelial progenitor cells from bone marrow during angiogenesis in adulthood (Zheng <i>et al.</i>). In addition to its role in hematopoiesis, the SDF-1α/CXCR4 signaling pathway is also essential for the homing of primordial germ cells to gonads (Ara <i>et al.</i> 2003b), the migration of granule cells in the cerebellum during neurogenesis (Zou <i>et al.</i>), and the migration of breast cancer cells to sites of metastasis (Muller <i>et al.</i>).

Leverancier: STEMCELL Technologies

Omschrijving: Vascular endothelial growth factor (VEGF-121) is a naturally-occurring VEGF-A splice variant involved in embryonic vasculogenesis and angiogenesis. VEGF binds to VEGFR-1 and VEGFR-2, and activates Raf/MEK/ERK and PI3K/AKT pathways. VEGF-121 is released as a freely diffusible protein by a variety of normal and transformed cells. It plays an important role in neurogenesis both in vitro and in vivo (Storkebaum <i>et al.</i>). It has neurotrophic effects on neurons of the central nervous system and promotes growth and survival of dopaminergic neurons and astrocytes. VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara <i>et al.</i>).

Leverancier: STEMCELL Technologies

Omschrijving: Amine-labelling fluorescent dye for live/dead staining of mammalian cells - 100 tests.