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Anti-TP53 Mouse Monoclonal Antibody (CF405S) [clone: DO-7]

Leverancier: Biotium
Omschrijving: Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Image Unavailable-BNUM0513-50

Anti-TP53 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: DO-7]

Catalogus nummer: (BNUM0513-50)
Leverancier: Biotium
Omschrijving: Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
UOM: 1 * 50 µl
Product Image-216-0405

Schalen, rond, lage vorm

Leverancier: NICKEL ELECTRO
Omschrijving: Pure nickel (99,6%).

Image Unavailable-PRSI33-344

Anti-AFP Mouse Monoclonal Antibody [clone: MBS-12]

Catalogus nummer: (PRSI33-344)
Leverancier: ProSci Inc.
Omschrijving: It recognises an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP). This mAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. The yolk sac and the liver produce AFP during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spinal bifida and anencephaly.
UOM: 1 * 1 EA

New Product


Product Image-221-0175

VWR®, Trechters met korte steel

Leverancier: VWR Collection
Omschrijving: Borosilicaat 3.3 glas.

Certificaten

Image Unavailable-APOSBIBE1004-5G

Poly(caprolactone-co-glycolide) 45:55

Catalogus nummer: (APOSBIBE1004-5G)
Leverancier: Apollo Scientific
Omschrijving: Polymer. Caprolactone:glycolide 45:55. Viscosity 1.5 dL/g
UOM: 1 * 5 g
Product Image-548-1935A

VWR®, Septa GL 45

Leverancier: VWR Collection
Omschrijving: VWR®, Septa, Red butyl/grey PTFE, Hardheid: 55° shore A, Dikte: 2,4 mm, Ø: 43,2 mm

Image Unavailable-TCIAE0266-500G

Ethyl cellulose, 45-55 mPa.s [5% in Toluene + Ethanol (80:20), 25 °C]

Leverancier: TCI
Omschrijving: Ethyl cellulose, 45-55 mPa.s [5% in Toluene + Ethanol (80:20), 25 °C]

Image Unavailable-APOSOR953494-250MG

4,5-Dichloroquinazoline 95%

Leverancier: Apollo Scientific
Omschrijving: 4,5-Dichloroquinazoline 95%

Image Unavailable-PRSI33-427

Anti-KRT7 Mouse Monoclonal Antibody [clone: KRT7/1198]

Catalogus nummer: (PRSI33-427)
Leverancier: ProSci Inc.
Omschrijving: It recognises an intermediate filament protein (IFP) of 55 kDa, which is identified as cytokeratin 7. This mAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This mAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
UOM: 1 * 1 EA

New Product


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2-Bromo-4,5-difluorobenzyl alcohol

Leverancier: Apollo Scientific
Omschrijving: 2-Bromo-4,5-difluorobenzyl alcohol

Product Image-BOCH3111

Double spatulas

Leverancier: BOCHEM
Omschrijving: Double-ended spatulas made of pure nickel (99,5%).

Image Unavailable-APOSOR451160-5G

1,4-Dioxaspiro[4.5]decane-8-carboxylic acid 95%

Leverancier: Apollo Scientific
Omschrijving: 1,4-Dioxaspiro[4.5]decane-8-carboxylic acid 95%

Image Unavailable-TCIAI0762-1G

(S)-(-)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone ≥98.0% (by HPLC, total nitrogen)

Leverancier: TCI
Omschrijving: (S)-(-)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone ≥98.0% (by HPLC, total nitrogen)

Product Image-NICK644

Dishes and lids

Leverancier: NICKEL ELECTRO
Omschrijving: Made of aluminium.

Image Unavailable-APOSOR8074-5G

4,5-Dichloro-6-methyl-2-(pyridin-2-yl)pyrimidine

Leverancier: Apollo Scientific
Omschrijving: 4,5-Dichloro-6-methyl-2-(pyridin-2-yl)pyrimidine

Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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